Related Experiment Video
Updated: Sep 25, 2025

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
Published on: August 22, 2022
Palaeoserology - teeth put into ancient plagues and pandemics
1Laboratory of Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Leuven, Belgium.
Abstract:
Based on archived medical records and evolutionary modelling, a Coronavirus has been hypothesized as root and causative agent of the so-called 'Russian Flu' pandemic that surged in 1889-1890. In a Correspondence published in this volume of Microbial Biotechnology, Ramassy and colleagues try to support historical evidence by true experimental data using 'palaeoserology', a novel approach combining archaeology and modern immunological analysis. This Opinion piece tries to weigh arguments how strong such data may be, and where a refinement of methodology might be desirable before textbooks of medical history switch to call the 1890s pandemic 'Russian Corona'.
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