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Updated: Sep 25, 2025

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
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CancelRx implementation: Observed changes to medication discontinuation workflows over time.

Taylor L Watterson1, Sara E Hernandez1, Jamie A Stone1

  • 1University of Wisconsin-Madison School of Pharmacy, Madison, WI, USA.

Exploratory Research in Clinical and Social Pharmacy
|April 28, 2022
PubMed
Summary
This summary is machine-generated.

CancelRx improved medication discontinuation workflows in outpatient pharmacies by streamlining pharmacist tasks. This health information technology reduced the need for pharmacists to investigate and document medication changes, enhancing efficiency.

Keywords:
CancelRxHealth ITMedication discontinuationWorkflow

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Area of Science:

  • Health Informatics
  • Pharmacy Practice
  • Medication Management

Background:

  • Medication discontinuations in outpatient clinics are often not effectively communicated to pharmacies.
  • This communication gap can lead to medication errors and suboptimal patient care.
  • CancelRx was developed to bridge this gap by electronically transmitting discontinuation messages from clinics to pharmacies.

Purpose of the Study:

  • To evaluate the impact of CancelRx on medication discontinuation workflows in outpatient pharmacies.
  • To understand pharmacists' perspectives on the implementation and effectiveness of CancelRx.
  • To identify changes in task frequency and patterns following CancelRx adoption.

Main Methods:

  • A collective case study approach was used at 3 UW Health outpatient pharmacies.
  • Comparative workflow modeling was employed before and after CancelRx implementation.
  • Pharmacists were observed at 3 time points (pre-implementation, 3 months post, 9 months post) with 106 discontinuation instances analyzed.

Main Results:

  • Implementation of CancelRx led to significant workflow changes.
  • Pharmacists largely eliminated the tasks of investigating and documenting discontinuation messages.
  • Task frequency and patterns shifted, indicating increased efficiency post-implementation.

Conclusions:

  • CancelRx positively impacted medication discontinuation workflows in outpatient pharmacies.
  • Proactive consideration of health information technology implications is crucial for successful implementation.
  • Anticipating workflow and practice changes can improve technology acceptance and effectiveness.