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Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Visible-light enabled room-temperature dealkylative imidation of secondary and tertiary amines promoted by aerobic
Dong Yang1, Jingqi Shi1, Jiaming Chen1
1Department of Pharmaceutical and Biological Engineering, School of Chemical Engineering, Sichuan University Chengdu 610065 China liziyuan@scu.edu.cn.
Abstract:
Employing sulfonyl azide as a nitrogen donor, a visible-light-enabled aerobic dealkylative imidation of tertiary and secondary amines involving C(sp3)-C(sp3) bond cleavage with moderate to excellent yields at room temperature is described. It has been demonstrated that this imidation could take place spontaneously upon visible-light irradiation, and could be facilitated considerably by a ruthenium photocatalyst and oxygen. An alternative mechanism to the previous aerobic photoredox pathway has also been proposed.
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