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Determining the frequency and level of task-sharing for hypertension management in LMICs: A systematic review and
Oluwabunmi Ogungbe1, Danielle Cazabon2, Adefunke Ajenikoko2
1Johns Hopkins University School of Nursing, Baltimore, MD, USA.
Insights
Team-based care significantly lowers systolic blood pressure (BP) in low- and middle-income countries. The effectiveness of hypertension management varies with the complexity of tasks performed by healthcare teams.
Area of Science:
- Cardiovascular Disease Research
- Global Health Initiatives
- Healthcare Management
Background:
- Low- and middle-income countries (LMICs) face a high burden of cardiovascular disease (CVD).
- Team-based care models enhance capacity for improving blood pressure (BP) control.
- This review assesses the efficacy of team-based care for hypertension across varying levels of complexity.
Purpose of the Study:
- To evaluate the effectiveness of team-based care in managing hypertension.
- To compare the impact of different levels of task complexity within healthcare teams on BP control.
- To synthesize evidence on task-sharing interventions for hypertension in LMICs.
Main Methods:
- Searched PubMed, Embase, Cochrane, and CINAHL for relevant studies.
- Categorized healthcare worker tasks into administrative (level 1), basic clinical (level 2), and advanced clinical (level 3).
- Conducted a meta-analysis of randomized controlled trials using a random-effects model to assess BP reduction compared to usual care.
Main Results:
- Included 43 randomized controlled trials (RCTs), with 12 from the updated search.
- Team-based care resulted in a pooled mean systolic BP reduction of -4.6 mm Hg (95% CI: -5.8, -3.4) compared to usual care.
- Reductions were consistent across complexity levels: -4.7 mm Hg for administrative/basic clinical tasks and -4.5 mm Hg for advanced clinical tasks. Pharmacists' involvement showed the greatest reduction (-7.3 mm Hg).
Conclusions:
- Team-based hypertension care consistently lowers systolic BP compared to usual care.
- The magnitude of BP reduction is influenced by the clinical training and roles of healthcare team members.
- Task-sharing interventions in LMICs demonstrate significant potential for improving hypertension management.
Background:
Low- and middle-income countries (LMICs) bear a disproportionately higher burden of Cardiovascular Disease (CVD). Team-based care approach adds capacity to improve blood pressure (BP) control. This updated review aimed to test team-based care efficacy at different levels of hypertension team-based care complexity.
Methods:
We searched PubMed, Embase, Cochrane, and CINAHL for newer articles on task-sharing interventions to manage hypertension in LMICs. Levels of tasks complexity performed by healthcare workers added to the clinical team in hypertension control programs were categorized as administrative tasks (level 1), basic clinical tasks (level 2), and/or advanced clinical tasks (level 3). Meta-analysis using an inverse variance weighted random-effects model summarized trial-based evidence on the efficacy of team-based care on BP control, compared with usual care.
Findings:
Forty-three RCT articles were included in the meta-analysis: 31 studies from the previous systematic review, 12 articles from the updated search. The pooled mean effect for team-based care was a -4.6 mm Hg (95% CI: -5.8, -3.4, I = 80.2%) decrease in systolic BP compared with usual care. We found similar comparative reduction among different levels of team-based care complexity, i.e., administrative and basic clinical tasks (-4.7 mm Hg, 95% CI: -6.8, -2.2; I = 79.8%); and advanced clinical tasks (-4.5 mmHg, 95%CI: -6.1, -3.3; I = 81%). Systolic BP was reduced most by team-based care involving pharmacists (-7.3 mm Hg, 95% CI: -9.2, -5.4; I = 67.2%); followed by nurses (-5.1 mm Hg, 95% CI: -8.0, -2.2; I = 72.7%), dieticians (-4.7 mmHg, 95%CI: -7.1, -2.3; I = 0.0%), then community health workers (-3.3 mm Hg, 95% CI: -4.8, -1.8; I = 77.3%).
Interpretation:
Overall, team-based hypertension care interventions consistently contributed to lower systolic BP compared to usual care; the effect size varies by the clinical training of the healthcare team members.
Funding:
Resolve To Save Lives (RTSL) Vital Strategies, Danielle Cazabon, Andrew E. Moran, Yvonne Commodore-Mensah receive salary support from Resolve to Save Lives, an initiative of Vital Strategies. Resolve to Save Lives is jointly supported by grants from Bloomberg Philanthropies, the Bill & Melinda Gates Foundation, and Gates Philanthropy Partners, which is funded with support from the Chan Zuckerberg Foundation.
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