[Physiosclerosis--arteriosclerosis. Progression and regression then and now]

The clinical recognition of the physiosclerosis is still problematic even nowadays. This question seems not to be actual, since the disease arteriosclerosis with all its sequels is the superior epidemiological problem of mankind. Therefore, the inhibition of the progression and the regression of arteriosclerosis is of great interest. Now as ever, however, the coming forth of an atheromatous focus into the blood stream and the later change of the ulcer developed in such a way into fibrous connective tissue is the only regression of the arteriosclerosis in man up to now certainly made evident. A new course is adopted. Three approaches of intervention are represented with own results: favourable effects of multiply unsaturated fatty acid, importance of the trace element balance, particularly of selenium, the use of the classical risk factor concept at all ages.