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Late bacterial endocarditis after percutaneous atrial septal defect closure

Makiko Nishioka1, Kenji Hoshino1, Shinya Ugaki2

  • 1Department of Pediatric Cardiology, Saitama Children's Medical Center, Saitama330-8777, Japan.

Cardiology in the Young
|April 28, 2022
PubMed

Insights

Infective endocarditis after percutaneous atrial septal defect closure is rare in children. This case highlights a late-stage infection in an 11-year-old girl due to incomplete device endothelialisation.

Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Infectious Diseases

Background:

  • Percutaneous closure of atrial septal defects (ASDs) is a common alternative to surgery.
  • Infective endocarditis is a known complication of cardiac occluding devices.
  • Late-stage endocarditis following pediatric ASD device closure is exceptionally rare.

Purpose of the Study:

  • To report a rare case of late-stage bacterial endocarditis in a child after percutaneous ASD closure.
  • To emphasize the importance of considering device-related complications even in pediatric patients.

Main Methods:

  • Case report of an 11-year-old girl.
  • Review of clinical presentation, diagnostic workup, and management.
  • Focus on the timeline of endocarditis development post-procedure.

Main Results:

  • The patient developed late-stage bacterial endocarditis.
  • The complication was linked to incomplete endothelialisation of the closure device.
  • This highlights a rare but serious potential adverse event.

Conclusions:

  • Late-stage infective endocarditis can occur following percutaneous ASD closure in children.
  • Incomplete endothelialisation may be a contributing factor.
  • Vigilance for device-related infections is crucial in pediatric cardiology.

Keywords:
Figulla Flex II OccluderInfective endocarditisatrial septal defectendothelialisationmethicillin-resistant Staphylococcus aureus

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