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Updated: Sep 25, 2025

Folding and Characterization of a Bio-responsive Robot from DNA Origami
Published on: December 3, 2015
Construction of Molecular Transporter Based on DNA Structure Regulation
Chengdong Ji1,2, Chunchun Yu3, Min Song4
1Zybio Inc, Chongqing, 400082, China.
Abstract:
This study aims to build a molecular transporter machine that is based on the microstructure regulation of DNA triplets, which can automatically search, load, target delivery, and unload target protein molecules. The design of the molecular transporter includes: (1) a DNA triplet, which can recognize and load of the target protein; (2) a similar DNA triplet realizing the target transport; and (3) the signal-indicating DNA, which is connected at the target destination to achieve fixation of the target protein at the target destination. The molecular transporter machine would provide research practice and theoretical guidance for the development of DNA-based molecular machines.
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