Related Experiment Video
Updated: Sep 25, 2025

Temporal Quantification of MAPK Induced Expression in Single Yeast Cells
Published on: October 4, 2013
Gene Co-Expression Network Analysis Reveals the Correlation Patterns Among Genes in Different Temperature Stress
Kifat Jahan1, Zhihui Yin1, Yanming Zhang1
1Engineering and Technology Research Center of Shellfish Breeding in Liaoning Province, College of Fisheries and Life Science, Dalian Ocean University, Dalian, 116023, China.
Abstract:
The Manila clam (Ruditapes philippinarum) is one of the most important aquaculture species and widely distributed along the coasts of China, Japan, and Korea. Due to its wide distribution, it can tolerate a wide range of temperature. Studying the gene expression profiles of clam gills had found differentially expressed genes (DEGs) and pathway involved in temperature stress tolerance. A systematic study of cellular response to temperature stress may provide insights into the mechanism of acquired tolerance. Here, weighted gene co-expression network analysis (WGCNA) was carried out using RNA-seq data from gill transcriptome in response to high and low temperature stress. There are a total 32 gene modules, of which 18 gene modules were identified as temperature-related modules. Blue module was one significantly correlated with temperature which was associated with cellular metabolism, apoptosis pathway, ER stress, and others.
Related Concept Videos
Constitutive and Regulated Gene Expression
Other Stress Responses in Bacteria
Responses to Heat and Cold Stress
Gene Regulation During Sporulation
Gene Regulation in Microbial Communities: Quorum Sensing
Cell Specific Gene Expression

