Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

6.2K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
6.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of a high-affinity anti-ROR1 variable region for broad anti-cancer immunotherapy.

Molecular therapy : the journal of the American Society of Gene Therapy·2025
Same author

An allele-resolved nanopore-guided tour of the human placental methylome.

Nature communications·2025
Same author

Mind the cap: Detecting degradation impurities in synthetic mRNAs.

Molecular therapy. Nucleic acids·2025
Same author

The design, manufacture and LNP formulation of mRNA for research use.

Nature protocols·2025
Same author

Targeted mRNA delivery with bispecific antibodies that tether LNPs to cell surface markers.

Molecular therapy. Nucleic acids·2025
Same author

Targeted DamID detects cell-type-specific histone modifications in intact tissues or organisms.

PLoS biology·2025
Same journal

Cross-Domain Transfer Learning from Peptides to Metabolites Using a Multi-Property Fine-Tuned LLM.

Bioinformatics (Oxford, England)·2026
Same journal

Biomedical Concept Recognition with Error-aware Negative-enhanced Ranking Framework.

Bioinformatics (Oxford, England)·2026
Same journal

TEDLH: Domain HMMs for sensitive detection of remote homologues.

Bioinformatics (Oxford, England)·2026
Same journal

PLNFGL: Joint Estimation of Multi-Condition Gene Networks from Single-cell RNA-seq Data.

Bioinformatics (Oxford, England)·2026
Same journal

MCFST: Spatial domain identification method based on multi-view graph convolutional network and graph fusion network.

Bioinformatics (Oxford, England)·2026
Same journal

SpaBiT: Enhancing Spatial Transcriptomics Resolution via Bidirectional Attention Transformers.

Bioinformatics (Oxford, England)·2026
See all related articles

Related Experiment Video

Updated: Sep 25, 2025

Nanopore DNA Sequencing for Metagenomic Soil Analysis
07:33

Nanopore DNA Sequencing for Metagenomic Soil Analysis

Published on: December 14, 2017

30.8K

Methylartist: tools for visualizing modified bases from nanopore sequence data.

Seth W Cheetham1, Michaela Kindlova2, Adam D Ewing1

  • 1Australian Institute for Bioengineering and Nanotechnology, University of Queensland, St Lucia, Australia.

Bioinformatics (Oxford, England)
|April 28, 2022
PubMed
Summary
This summary is machine-generated.

Methylartist is a new Python tool for analyzing nanopore-derived modified base calls, supporting multiple methylation types like 5mCpG, 5hmC, and 6mA for integrated studies.

More Related Videos

Author Spotlight: A Cost-Effective Genomic Workflow for Advancing Rabies Control in Resource-Limited Settings
10:26

Author Spotlight: A Cost-Effective Genomic Workflow for Advancing Rabies Control in Resource-Limited Settings

Published on: August 18, 2023

5.6K
Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance
04:58

Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance

Published on: December 13, 2024

3.0K

Related Experiment Videos

Last Updated: Sep 25, 2025

Nanopore DNA Sequencing for Metagenomic Soil Analysis
07:33

Nanopore DNA Sequencing for Metagenomic Soil Analysis

Published on: December 14, 2017

30.8K
Author Spotlight: A Cost-Effective Genomic Workflow for Advancing Rabies Control in Resource-Limited Settings
10:26

Author Spotlight: A Cost-Effective Genomic Workflow for Advancing Rabies Control in Resource-Limited Settings

Published on: August 18, 2023

5.6K
Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance
04:58

Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance

Published on: December 13, 2024

3.0K

Area of Science:

  • Bioinformatics
  • Genomics
  • Epigenetics

Background:

  • Nanopore sequencing technology enables direct detection of base modifications.
  • Analyzing modified base calls, such as methylation, requires specialized bioinformatics tools.
  • Current tools may not offer integrated analysis of diverse methylation types.

Purpose of the Study:

  • To introduce Methylartist, a comprehensive software suite for processing and analyzing nanopore-derived modified base calls.
  • To provide a unified platform for studying various types of DNA and RNA methylation.

Main Methods:

  • Methylartist is a Python-based suite.
  • It supports the analysis of multiple detectable methylation types, including 5mCpG, 5hmC, and 6mA.
  • The tool facilitates visualization and analysis of modified base calls from nanopore sequencing data.

Main Results:

  • Methylartist enables the integrated study of different base modifications.
  • It supports both naturally occurring and experimentally induced modifications.
  • The software provides a consolidated approach to analyzing complex epigenomic data.

Conclusions:

  • Methylartist offers a versatile solution for nanopore-based epigenomic research.
  • The tool enhances the ability to study diverse methylation patterns comprehensively.
  • It is readily available for the scientific community via PyPI and bioconda.