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Too Sensitive or Just Right?

Dana Martin1, Steven C Smith1,2, Alden Chesney1

  • 1Department of Pathology, Virginia Commonwealth University (VCU) School of Medicine, Richmond, VA, USA.

American Journal of Clinical Pathology
|April 28, 2022
PubMed
Summary

The D5F3 antibody clone demonstrated superior performance in detecting anaplastic large cell lymphoma (ALCL) compared to the ALK1 clone, showing greater staining intensity and proportion. This finding is crucial for accurate ALCL diagnosis, especially with limited tissue samples.

Keywords:
ALCLALKAnaplastic large cell lymphomaAnaplastic lymphoma kinaseFISHFluorescence in situ hybridizationIHCImmunohistochemistry

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