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Hypertensive Disorders in Pregnancy and Mortality at Delivery Hospitalization - United States, 2017-2019
Insights
Hypertensive disorders in pregnancy (HDPs) are increasingly common, affecting 15.9% of deliveries by 2019. Prompt identification and equitable treatment are crucial to prevent severe maternal complications and deaths.
Area of Science:
- Obstetrics and Gynecology
- Public Health
- Cardiovascular Medicine
Background:
- Hypertensive disorders in pregnancy (HDPs) are common and linked to severe maternal complications and mortality.
- HDPs include chronic hypertension and pregnancy-associated hypertension.
- These conditions are a leading cause of pregnancy-related deaths in the US.
Purpose of the Study:
- To analyze the prevalence of HDPs among delivery hospitalizations in the US from 2017-2019.
- To examine HDP prevalence by maternal characteristics and geographic regions.
- To determine the percentage of in-hospital deaths associated with HDP.
Main Methods:
- Analysis of nationally representative data from the National Inpatient Sample (2017-2019).
- Calculation of annual prevalence of HDPs and specific types (pregnancy-associated, chronic).
- Examination of HDP prevalence across demographic groups and hospital locations.
Main Results:
- Overall HDP prevalence increased from 13.3% to 15.9% between 2017 and 2019.
- Pregnancy-associated hypertension rose from 10.8% to 13.0%; chronic hypertension from 2.0% to 2.3%.
- Highest HDP prevalence observed in Black, AI/AN women, older mothers, low-income areas, and the South/Midwest regions. 31.6% of delivery-related deaths had documented HDP.
Conclusions:
- HDPs represent a growing public health concern in US pregnancies.
- Disparities in HDP prevalence highlight the need for targeted interventions.
- Equitable implementation of monitoring and timely treatment strategies can reduce severe HDP complications and mortality.
Abstract:
Hypertensive disorders in pregnancy (HDPs), defined as prepregnancy (chronic) or pregnancy-associated hypertension, are common pregnancy complications in the United States.* HDPs are strongly associated with severe maternal complications, such as heart attack and stroke (1), and are a leading cause of pregnancy-related death in the United States.† CDC analyzed nationally representative data from the National Inpatient Sample to calculate the annual prevalence of HDP among delivery hospitalizations and by maternal characteristics, and the percentage of in-hospital deaths with an HDP diagnosis code documented. During 2017-2019, the prevalence of HDP among delivery hospitalizations increased from 13.3% to 15.9%. The prevalence of pregnancy-associated hypertension increased from 10.8% in 2017 to 13.0% in 2019, while the prevalence of chronic hypertension increased from 2.0% to 2.3%. Prevalence of HDP was highest among delivery hospitalizations of non-Hispanic Black or African American (Black) women, non-Hispanic American Indian and Alaska Native (AI/AN) women, and women aged ≥35 years, residing in zip codes in the lowest median household income quartile, or delivering in hospitals in the South or the Midwest Census regions. Among deaths that occurred during delivery hospitalization, 31.6% had any HDP documented. Clinical guidance for reducing complications from HDP focuses on prompt identification and preventing progression to severe maternal complications through timely treatment (1). Recommendations for identifying and monitoring pregnant persons with hypertension include measuring blood pressure throughout pregnancy,§ including self-monitoring. Severe complications and mortality from HDP are preventable with equitable implementation of strategies to identify and monitor persons with HDP (1) and quality improvement initiatives to improve prompt treatment and increase awareness of urgent maternal warning signs (2).
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