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Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
Published on: April 20, 2018
[Advances in risk factors and genetic risk of head and neck squamous cell carcinoma]
Xiaomin Tu1, Jianjun Ren2, Yu Zhao2
1Department of Otolaryngology Head and Neck Surgery,Chengdu Fifth People's Hospital,Chengdu,611130,China.
Abstract:
With the incidence of head and neck squamous cell carcinoma increasing year by year and the epidemiological trend changes, the research on risk factors of head and neck squamous cell carcinoma and its primary prevention has attracted more and more attention. At present, many risk factors of head and neck squamous cell carcinoma have been studied, which can be divided into genetic factors and non-genetic factors. Among the non-genetic factors, viral infection (HPV virus, Epstein-Barr virus), lifestyle (smoking, drinking, diet, chewing betel nut), social behavior factors, immunosuppression, occupational exposure, and other factors are closely related to HNSCC incidence. In this paper, the research progress of HNSCC related risk factors is reviewed to provide evidence for the identification of the risk of head and neck squamous cell carcinoma and reduce the risk behaviors to reduce the incidence of head and neck squamous cell carcinoma.
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