Related Experiment Video

Updated: Sep 25, 2025

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults
04:14

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults

Published on: February 28, 2025

250

[Three cases of urachal cyst in adults]

Lorena Alarcón-Molero1, Carolina Martínez-Ciarpaglini1, Victor Puglia2

  • 1Servicio de Anatomía Patológica, Hospital Clínico Universitario de Valencia, Valencia, España.

Revista Espanola De Patologia : Publicacion Oficial De La Sociedad Espanola De Anatomia Patologica Y De La Sociedad Espanola De Citologia
|April 28, 2022
PubMed

Insights

Urachal cysts, rare in adults, arise from incomplete obliteration of the fetal allantois. Definitive diagnosis relies on histopathology, distinguishing them from other abdominal cysts.

Area of Science:

  • Urology
  • Pathology
  • Developmental Biology

Background:

  • The urachus, a remnant of the allantois, typically obliterates by the fifth month of gestation.
  • Urachal cysts result from incomplete obliteration of this duct, being uncommon in adults.

Observation:

  • Three adult cases of urachal cysts are presented.
  • One case was diagnosed during investigation for abdominal pain; two were incidental findings.
  • Clinical suspicion was present in all cases.

Findings:

  • Histologically, urachal cysts exhibit urothelial-type epithelium.
  • Immunohistochemistry shows expression of CK7, CK20, CK5/6, P63, and GATA3.
  • These markers aid in differentiating urachal cysts from other abdominal cystic lesions.

Implications:

  • Highlights the importance of considering urachal cysts in adult abdominal pathology.
  • Emphasizes the diagnostic utility of histopathology and immunohistochemistry.
  • Aids in accurate differential diagnosis of cystic abdominal masses in adults.

Keywords:
Anomalías uracalesCystic lesionsHistologyHistologíaLesiones quísticasQuiste de uracoUrachal anomaliesUrachal cyst

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