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Alterations in intestinal microbiota in ultramarathon runners
1Juntendo University Graduate School of Health and Sports Science, 1-1, Hiragagakuendai, Inzai, Chiba, 270-15, Japan.
Scientific Reports
|April 28, 2022
Summary
Ultramarathon running significantly decreases beneficial butyrate-producing gut bacteria. This reduction in gut microbiota may impact immune function and lead to symptoms like fatigue and poor sleep in athletes.
Area of Science:
- Microbiology
- Human Physiology
- Sports Science
Background:
- Limited research exists on gut microbiome changes in ultramarathon runners.
- Previous studies suggest endurance exercise can alter gut microbiota composition.
Purpose of the Study:
- To investigate the impact of ultramarathon running on intestinal microbiota composition and diversity.
- To identify specific bacterial changes and their potential physiological consequences in ultramarathon athletes.
Main Methods:
- Analysis of intestinal microbiota in nine ultramarathon runners at three time points: pre-race, post-race, and 10-day recovery.
- Assessment of alpha and beta diversity, enterotypes, and abundance of specific bacterial species, including Faecalibacterium prausnitzii.
Main Results:
- Ultramarathon running did not significantly alter alpha or beta diversity of the gut microbiota.
- A significant decrease in the abundance of Faecalibacterium prausnitzii and other butyrate-producing bacteria was observed post-race.
- One participant with the largest decrease in F. prausnitzii reported fatigue and sleep disturbances during recovery.
Conclusions:
- Ultramarathon running leads to a reduction in butyrate-producing bacteria, potentially lowering intestinal butyrate levels.
- Decreased butyrate may affect host immune function and contribute to adverse physiological effects in ultramarathon runners.
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