[Asthenic syndrome in general therapeutic practice].

Area of Science:

• Physiology
• Pathophysiology
• Pharmacology

Background:

• Asthenia is a universal protective mechanism linked to energy deficiency in psychophysiological processes and somatic diseases.
• Asthenic syndrome (AS) arises from diverse etiological factors and manifests in various clinical forms.
• Understanding the underlying energy deficiency mechanisms is crucial for addressing asthenia.

Purpose of the Study:

• To explore the role of asthenia as a protective mechanism.
• To discuss the etiological factors and clinical presentations of asthenic syndrome.
• To evaluate the potential of L-carnitine for correcting asthenic syndrome.

Main Methods:

• Review of existing literature on asthenia and asthenic syndrome.
• Analysis of etiological factors contributing to asthenic syndrome.
• Examination of carnitine's pharmacological effects relevant to asthenia.

Main Results:

• Asthenia functions as a protective response associated with energy deficits.
• Asthenic syndrome exhibits varied clinical forms based on its origin.
• Carnitine demonstrates key effects that may help in managing asthenia.

Conclusions:

• Asthenia is a significant physiological response to energy deficiency.
• L-carnitine preparations are a potential therapeutic option for asthenic syndrome.
• L-carnitine can be used in monotherapy or polytherapy for asthenic syndrome correction.