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Updated: Sep 25, 2025

Estimation of Urinary Nanocrystals in Humans using Calcium Fluorophore Labeling and Nanoparticle Tracking Analysis
Published on: February 9, 2021
[Molecular genetic predictors of the development of urolithiasis]
D N Khotko1,2, N V Polukonova1,2, A I Khotko1,2
1FGAOU VO Saratov State Medical University named after V. I. Razumovsky, Ministry of Health of Russia, Saratov, Russia.
Abstract:
Urolithiasis is one of the most urgent problems of clinical urology. Currently, there is no consensus on the causes of stone formation, as well as the role of various factors in the development of urolithiasis, however, increasingly, according to various studies, the leading role is given to genetic causes. The article presents a modern review of data on genetic polymorphisms associated with ICD: rs1801197 and rs6776158 of the CASR gene; TaqI of the VDR gene; rs1801197 of the CALCR gene, rs3752472, rs650439, rs2853744 of the Klotho gene.
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