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Related Experiment Video

Updated: Sep 25, 2025

Multispectral Optoacoustic Tomography for Functional Imaging in Vascular Research
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Imaging-photoplethysmography-guided optical microangiography.

Qinghua He, Ruikang K Wang

    Optics Letters
    |April 29, 2022
    PubMed
    Summary

    We developed a new method combining imaging photoplethysmography (iPPG) and optical coherence tomography (OCT) to visualize facial skin blood flow. This technique guides imaging for better assessment of skin conditions.

    Area of Science:

    • Biomedical Optics
    • Dermatology
    • Medical Imaging

    Background:

    • Assessing cutaneous microvascular perfusion is crucial for diagnosing skin conditions.
    • Current imaging techniques may lack the resolution or field of view for comprehensive microvascular analysis.

    Purpose of the Study:

    • To introduce a novel method for imaging facial cutaneous microvascular perfusion.
    • To demonstrate the utility of integrating wide-field imaging photoplethysmography (iPPG) with handheld swept-source optical coherence tomography (OCT).

    Main Methods:

    • Utilized a 16-bit-depth camera for wide-field iPPG to generate a 2D blood pulsation map.
    • Employed the iPPG map as a guidance system for targeted OCT imaging of cutaneous microvasculature.
    • Acquired and analyzed iPPG and OCT data from facial skin.

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    Main Results:

    • Successfully demonstrated guided imaging of facial cutaneous microvasculature using the combined iPPG-OCT system.
    • The iPPG system provided effective positioning guidance for high-resolution OCT imaging.
    • The results showcase the capability of visualizing microvascular dynamics in the skin.

    Conclusions:

    • The integrated iPPG and OCT method offers a promising approach for non-invasive imaging of facial microvascular perfusion.
    • This technique has potential applications in dermatology and cosmetology for assessing skin health and conditions.
    • Guided imaging enhances the precision and relevance of microvascular assessments.