Related Experiment Video

Updated: Sep 25, 2025

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma
10:58

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

Published on: February 22, 2015

13.1K

Epigenetic STING silencing is developmentally conserved in gliomas and can be rescued by methyltransferase inhibition

Justin T Low1, Vidyalakshmi Chandramohan1, Michelle L Bowie1

  • 1Department of Neurosurgery, Duke University Medical School, Durham, NC, USA.

Cancer Cell
|April 29, 2022
PubMed
Abstract

No abstract available in PubMed .

More Related Videos

Native Chromatin Immunoprecipitation Using Murine Brain Tumor Neurospheres
09:31

Native Chromatin Immunoprecipitation Using Murine Brain Tumor Neurospheres

Published on: January 29, 2018

7.8K
Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models
13:47

Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models

Published on: March 29, 2019

9.8K

Related Experiment Videos

Last Updated: Sep 25, 2025

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma
10:58

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

Published on: February 22, 2015

13.1K
Native Chromatin Immunoprecipitation Using Murine Brain Tumor Neurospheres
09:31

Native Chromatin Immunoprecipitation Using Murine Brain Tumor Neurospheres

Published on: January 29, 2018

7.8K
Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models
13:47

Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models

Published on: March 29, 2019

9.8K

Related Concept Videos

Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

35.4K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
35.4K
Epigenetic Regulation01:46

Epigenetic Regulation

31.4K
Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
31.4K

Articles linked to this work by shared authors, journal, and citation graph.

EGFR-targeted antibody-toxin conjugate in recurrent glioma: a phase 1 trial.

Nature medicine·2026

Divergent genomic evolution in astrocytomas and oligodendrogliomas.

Nature·2026

Automated imaging response evaluation system: Prototype software tool for standardized radiographic response assessment in glioblastoma clinical trials.

Neuro-oncology practice·2026

DNA-PKcs inhibition sensitizes glioblastoma to radiotherapy through reprogramming of tumor cell states and immune microenvironment cell types.

Research square·2026

Epstein-Barr Virus-Positive Primary CNS Lymphoma in a Patient Receiving Mycophenolate Mofetil: Diagnostic and Therapeutic Considerations.

Viruses·2026

Anti-VEGF vascular remodeling drives germinal center B cell-rich tertiary lymphoid structures during antibody-toxin and anti-CD40 combination therapy in glioblastoma.

Research square·2026

CPS + EG and Neo-Bioscore predict individual outcomes but not trial results after neoadjuvant therapy for early breast cancer.

Cancer cell·2026

Antibiotics and outcomes of cancer immunotherapy: An updated meta-analysis and clinical applications.

Cancer cell·2026

Macrophage lipid signaling drives glioblastoma invasion and represents a therapeutic vulnerability.

Cancer cell·2026

Finding MES: A hidden cell state in neuroblastoma.

Cancer cell·2026

Lung neuroendocrine cancer induces immunosuppressive macrophages via serotonin to drive resistance to the T cell engager tarlatamab.

Cancer cell·2026

How far are we from multi-omics states to therapeutic targets in microsatellite-stable colorectal cancer?

Cancer cell·2026

Modifiable adiposity-related risk for chronic kidney disease in APOL1 variant carriers: Pilot study results.

Nutrition and health·2026

Genomic profiling of microphthalmia trios reveals novel pathogenic drivers and repetitive element instability.

Human molecular genetics·2026

Complete circular genome sequence of an acne-associated Cutibacterium namnetense clinical isolate.

Microbiology resource announcements·2026

FAM60A Regulates SIN3A-HDAC Complex Activity to Induce G1/S Phase Arrest and Promote Differentiation of Low-Grade Glioma.

Biology of the cell·2026

Single-Cell Transcriptomic Analysis Reveals Age-Associated Cellular and Transcriptional Changes in Murine Lacrimal Glands.

Investigative ophthalmology & visual science·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us