Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

194
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
194

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

HERA: a web server for host element reference-based aligner.

Nucleic acids research·2026
Same author

RegRegSEA: a web server for regulatory region set enrichment analysis of epigenomic data.

Nucleic acids research·2026
Same author

mRNA Sequencing of Limbal Epithelial Cells and mRNA/miRNA Profiling of Limbal Stromal Cells in <i>PAX6</i>-Related Congenital Aniridia.

Cells·2026
Same author

MCPmed: a call for Model Context Protocol-enabled bioinformatics web services for LLM-driven discovery.

Briefings in bioinformatics·2026
Same author

MiRNAs shape mouse age-independent tissue adaptation to spaceflight via ECM and developmental pathways.

Nature communications·2026
Same author

Ageing promotes microglial accumulation of slow-degrading synaptic proteins.

Nature·2026

Related Experiment Video

Updated: Sep 25, 2025

Empirical, Metagenomic, and Computational Techniques Illuminate the Mechanisms by which Fungicides Compromise Bee Health
08:36

Empirical, Metagenomic, and Computational Techniques Illuminate the Mechanisms by which Fungicides Compromise Bee Health

Published on: October 9, 2017

9.9K

BusyBee Web: towards comprehensive and differential composition-based metagenomic binning.

Georges P Schmartz1, Pascal Hirsch1,2, Jérémy Amand1,2

  • 1Chair for Clinical Bioinformatics, Saarland University, 66123 Saarbrücken, Germany.

Nucleic Acids Research
|April 30, 2022
PubMed
Summary

BusyBee Web enhances metagenomic analysis with improved genomic binning, offering new visualizations and plasmid detection. This updated tool facilitates differential analysis and automated workflows for researchers.

More Related Videos

Efficient Nucleic Acid Extraction and 16S rRNA Gene Sequencing for Bacterial Community Characterization
12:37

Efficient Nucleic Acid Extraction and 16S rRNA Gene Sequencing for Bacterial Community Characterization

Published on: April 14, 2016

39.0K
Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

29.8K

Related Experiment Videos

Last Updated: Sep 25, 2025

Empirical, Metagenomic, and Computational Techniques Illuminate the Mechanisms by which Fungicides Compromise Bee Health
08:36

Empirical, Metagenomic, and Computational Techniques Illuminate the Mechanisms by which Fungicides Compromise Bee Health

Published on: October 9, 2017

9.9K
Efficient Nucleic Acid Extraction and 16S rRNA Gene Sequencing for Bacterial Community Characterization
12:37

Efficient Nucleic Acid Extraction and 16S rRNA Gene Sequencing for Bacterial Community Characterization

Published on: April 14, 2016

39.0K
Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

29.8K

Area of Science:

  • Metagenomics
  • Bioinformatics
  • Computational Biology

Background:

  • Metagenomic assembly and genomic binning are crucial for analyzing mixed microbial communities, especially when reference genomes are unavailable.
  • Genomic binning, a state-of-the-art method, aids in dissecting complex metagenomic data.
  • BusyBee Web was previously established as an efficient, composition-based binning webserver.

Purpose of the Study:

  • To enhance the BusyBee Web tool with advanced features for metagenomic data analysis.
  • To improve user experience and expand analytical capabilities for researchers.
  • To provide automated access and integration options for power users.

Main Methods:

  • The study involved revisiting and updating the existing BusyBee Web functionality.
  • New comprehensive visualizations and increased data analysis customization options were added.
  • Implementation of a new application programming interface (API) with a Python package for automated access.

Main Results:

  • The updated BusyBee Web now supports visualization-supported differential analysis of metagenomic samples.
  • Users can optionally screen samples for plasmid sequences using the PLSDB reference database.
  • An API and Python package enable automated workflows and integration for advanced users.

Conclusions:

  • BusyBee Web has been significantly upgraded, offering enhanced capabilities for metagenomic analysis.
  • The tool now provides more sophisticated analysis options, including differential analysis and plasmid detection.
  • The new API facilitates seamless integration into existing bioinformatics pipelines.