Hamlet and radiology
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Updated: Sep 25, 2025

Autoradiography as a Simple and Powerful Method for Visualization and Characterization of Pharmacological Targets
Published on: March 12, 2019
1Department of Radiology, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey; Department of Radiology, Dr. AY Ankara Oncology Training and Research Hospital, Ankara, Turkey..
Abstract:
After I started my radiology training, searching for art in radiology became a passion for me. One of the most concrete examples of my search was a case of CT-guided biopsy we encountered recently. In a patient with metastatic cancer, we searched for the primary lesion. PET/CT showed a focus in the upper lobe of the right lung. During the CT-guided biopsy, this lesion was like a smiling face in shape. The fact that this cute-looking mass was metastatic cancer reminded me of a character from Hamlet. In William Shakespeare's famous work, Prince Hamlet refers to Claudius as a 'smiling villain' and draws attention to the evil behind his smile. In this article, we discuss the similarity of our daily practice with Hamlet through a case.
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