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Updated: Sep 25, 2025

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
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Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism

Published on: July 28, 2017

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A protocol to replace dedication to either normal phase or polar organic mode for chiral stationary phases containing

Simon Horváth1, Zsuzsanna Eke2, Gábor Németh3

  • 1György Hevesy Doctoral School of Chemistry, Eötvös Loránd University, Pázmány Péter stny. 1/A, H-1117, Budapest, Hungary; Drug Substance Development Division, Egis Pharmaceuticals PLC, P. O. Box 100, H-1475, Budapest, Hungary.

Journal of Chromatography. A
|May 1, 2022
PubMed

Keywords:
Chiral HPLCEluent historyHindered structural transitionMode dedicationRegeneration of chiral stationary phases

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