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Extraction and Analysis of Taiwanese Green Propolis
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Method to prepare aqueous propolis dispersions based on phase separation.

Julien Monteil1, Abdessattar Hadj-Sassi1, Élise Dargelos1

  • 1Université de Bordeaux, CNRS, Bordeaux INP, CBMN UMR 5248, 33600 Pessac, France.

Food Chemistry
|May 1, 2022
PubMed
Summary
This summary is machine-generated.

Researchers developed stable propolis-in-water dispersions for oral nutraceutical use. This method creates micron-sized propolis droplets, enhancing health benefits and consumption.

Keywords:
EmulsionNutraceuticalParticle sizePhase separationPropolis

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Area of Science:

  • Food Science
  • Nutraceutical Development
  • Colloid and Interface Science

Background:

  • Propolis offers significant health benefits but lacks convenient oral consumption methods.
  • Existing propolis formulations may not be optimally bioavailable or stable for nutraceutical applications.

Purpose of the Study:

  • To develop stable, orally consumable propolis-in-water dispersions for nutraceutical purposes.
  • To characterize the phase behavior of propolis, water, and ethanol to optimize dispersion formation.

Main Methods:

  • Exploration of the ternary phase diagram of propolis, water, and ethanol.
  • Induction of phase separation and droplet formation using mechanical stirring (rotor-stator, microfluidizer).
  • Stabilization of propolis droplets with gum Arabic and removal of ethanol via reduced pressure distillation.

Main Results:

  • Successful creation of propolis-in-water dispersions with micron and submicron droplet sizes.
  • Obtained dispersions contained 1.75–10.5 wt% polyphenols relative to total mass.
  • Identified phase boundaries for controlled propolis dissolution and precipitation.

Conclusions:

  • A novel method for producing stable propolis-in-water dispersions suitable for nutraceuticals was established.
  • The developed dispersions offer enhanced oral delivery of propolis's health-promoting compounds.
  • This formulation strategy addresses limitations in current propolis-based health products.