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Cardiac complications of COVID-19: Incidence and outcomes
Jayasree Pillarisetti1, Mubeen S Cheema1, Justin Haloot1
1Division of Cardiology, University of Texas Health San Antonio, USA.
Insights
Patients with COVID-19 experiencing cardiac complications, such as heart failure or atrial fibrillation, face a significantly higher mortality risk. Older males are particularly vulnerable to these cardiovascular issues and death.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- Coronavirus disease-2019 (COVID-19) is linked to cardiac conditions and cardiovascular complications.
- The incidence of these cardiac issues, along with age and gender disparities, remains unclear in COVID-19 patients.
Purpose of the Study:
- To determine the incidence of cardiac complications in patients diagnosed with COVID-19.
- To investigate the mortality rates associated with these cardiac complications.
Main Methods:
- Utilized data from the TriNetX COVID-19 global research network.
- Compared outcomes and survival data between COVID-19 patients with and without cardiac complications.
Main Results:
- A cohort of 81,844 COVID-19 patients was analyzed.
- Cardiac complications affected 9.3% of patients, including acute coronary syndromes (1.3%), heart failure (4.4%), and atrial fibrillation (4.5%).
- Mortality was substantially higher in patients with cardiac complications (20%) versus those without (2.9%), with older males showing increased risk.
Conclusions:
- COVID-19 patients with cardiac complications exhibit a significantly elevated risk of mortality.
- Identifying and managing cardiac complications is crucial for improving outcomes in COVID-19 patients.
Background:
Coronavirus disease-2019 (COVID-19) has been associated with pre-existing cardiac conditions as well as cardiovascular complications. The incidence rates of cardiac complications, age, and gender differences in this population are unknown.
Objectives:
We wanted to study the incidence of cardiac complications and mortality in patients with COVID-19.
Methods:
Data from the TriNetX COVID-19 global research network platform was used to identify COVID-19 patients. We compared patients with and without cardiac complications in patients with COVID-19 and obtained survival data.
Results:
The final cohort was composed of 81,844 patients with COVID-19. Cardiac complications occurred in 9.3% of patients as follows: acute coronary syndromes in 1.3%, heart failure in 4.4%, atrial fibrillation in 4.5%, sinus bradycardia 1.9%, ventricular tachycardia in 0.5% and complete heart block in 0.01%. Mortality was significantly higher in patients with the cardiac complications mentioned (20%) than in those without them (2.9%) (odds ratio 7.2, 95% CI, 6.7-7.7; p < 0.0001). Older males seem to have higher incidence of cardiac complications and mortality.
Conclusions:
Patients with COVID-19 who have cardiac complications have a higher risk of mortality when compared to those without cardiac complications.
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