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Updated: Sep 25, 2025

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A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
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Future Treatments in Melanoma.
Kathryn Wells1, Vinesh Anandarajan1, James Nitzkorski1
1Department of Surgery, Vassar Brothers Medical Center, Nuvance Health, Dyson Center for Cancer Care, 45 Reade Place, 3rd Floor Surgical Oncology, Poughkeepsie, NY 12601, USA.
Summary
Surgical removal remains the primary treatment for melanoma, a common U.S. cancer. However, integrating immune and targeted therapies is crucial for managing this complex malignancy.
Area of Science:
- Oncology
- Surgical Oncology
- Dermatology
Background:
- Melanoma is a prevalent and highly malignant skin cancer in the United States.
- While surgical resection is the standard treatment, advancements necessitate updated therapeutic strategies.
Purpose of the Study:
- To highlight the evolving role of multimodal therapy in melanoma treatment.
- To inform head and neck surgeons about contemporary melanoma management.
Main Methods:
- Review of current therapeutic approaches for melanoma.
- Emphasis on the integration of novel treatment modalities.
Main Results:
- Surgical extirpation remains the cornerstone of melanoma management.
- Immune and targeted therapies are increasingly vital components of multimodal treatment plans.
Conclusions:
- Multimodal therapy, including surgery and novel agents, is reshaping melanoma treatment.
- Head and neck surgeons must adapt to these advancements for optimal patient outcomes.
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