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Constipation Is a Frequent Problem Associated with Vascular Complications in Patients with Type 2 Diabetes: A
Hiroyuki Ito1, Kiyoko Ito2, Mahika Tanaka2
1Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital, Japan.
Constipation affects 36% of Japanese type 2 diabetes patients, often linked to older age, longer diabetes duration, and increased risk of coronary heart disease (CHD). Accurate diagnosis is crucial for managing this common comorbidity.
Area of Science:
- Endocrinology and Metabolism
- Gastroenterology
Background:
- Diabetes mellitus is a known risk factor for constipation.
- Prevalence of constipation in diabetic patients varies with diagnostic criteria.
- New guidelines for constipation diagnosis exist for Japanese populations.
Purpose of the Study:
- To determine the prevalence of constipation in Japanese type 2 diabetes patients using new guidelines.
- To examine the association between constipation and clinical factors, including diabetic vascular complications.
Main Methods:
- Questionnaire surveys administered to 410 Japanese patients with type 2 diabetes.
- Inclusion of self-judged constipation, physician consultations, and laxative use in prevalence assessment.
- Analysis of clinical background, including body mass index (BMI), diabetic neuropathy, and coronary heart disease (CHD).
Main Results:
- Overall constipation prevalence (chronic constipation or laxative use) was 36%.
- Constipated patients were older, had longer diabetes duration, and lower BMI.
- Diabetic neuropathy and CHD were significantly more frequent in patients with constipation.
Conclusions:
- Constipation is prevalent in Japanese type 2 diabetes patients, affecting 36% even with laxative use.
- Constipation is independently associated with coronary heart disease (CHD) in this population.
- Accurate diagnosis and management of constipation are important in type 2 diabetes care.
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