Related Experiment Video
Updated: Sep 25, 2025
10:49
Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
Published on: September 18, 2013
18.3K
[Radiotherapy for the treatment of leukemia].
Michael Oertel1, Hans Theodor Eich1
1Albert-Schweitzer-Campus 1, Gebäude A1, 48149 Münster, Deutschland Klinik für Strahlentherapie - Radioonkologie, Universitätsklinikum Münster.
Der Gynakologe
|May 2, 2022
Summary
Radiation therapy, including total body irradiation, is a key treatment for leukemia, offering manageable side effects. Ongoing research aims to improve targeting for better outcomes in leukemia patients.
Area of Science:
- Oncology
- Radiotherapy
Context:
- Lymphoma cells' radiosensitivity supports radiation therapy in leukemia treatment.
- Total body irradiation (TBI) is an established conditioning regimen for allogeneic stem cell transplantation.
Purpose:
- To provide an overview of radiation therapy execution and side effects in leukemia.
- To specifically detail long-term side effects following TBI.
Summary:
- TBI is effective for conditioning before stem cell transplantation, with a manageable toxicity profile including long-term effects.
- Low-dose radiotherapy can treat myeloid sarcoma (chloroma).
Impact:
- Interdisciplinary, long-term aftercare is crucial for managing TBI side effects.
- Emerging techniques for more selective targeting are under clinical evaluation.
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