Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Focusing of Light in the Eye01:16

Focusing of Light in the Eye

3.3K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correlation Between Accommodative Facility and Light-Evoked Pupil Responses in Individuals with History of Mild Traumatic Brain Injury.

Journal of eye movement research·2026
Same author

AUBADE-syn: a novel deep learning ensemble method for glaucoma detection using synthetic fundus images on imbalanced datasets.

NPJ digital medicine·2026
Same author

Adaptive Temporal Mixture of Experts for Predicting Stiffness Metrics From the Ocular Response Analyzer and Identifying Keratoconus.

American journal of ophthalmology·2026
Same author

Best Practices for High-Quality Anterior Segment Optical Coherence Tomography Imaging of Eyes with the Port Delivery Platform Implant.

Diagnostics (Basel, Switzerland)·2025
Same author

Contact lenses and digital eye strain.

Clinical & experimental optometry·2025
Same author

New Framework for Classical Double Copies.

Physical review letters·2025

Related Experiment Video

Updated: Sep 25, 2025

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
08:22

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

4.5K

Foveal Phase Retardation Correlates With Optically Measured Henle Fiber Layer Thickness.

Phillip T Yuhas1, Marisa L Ciamacca1, Keith A Ramsey1

  • 1College of Optometry, The Ohio State University, Columbus, OH, United States.

Frontiers in Medicine
|May 2, 2022
PubMed
Summary

Scanning laser polarimetry revealed a strong correlation between phase retardation and Henle fiber layer (HFL) thickness in the macula. This confirms HFL as the primary source of the phase retardation signal in the central macula.

Keywords:
Henle fiber layerdirectional optical coherence tomographyfoveamacula HFL thicknessphase retardationscanning laser polarimetry

More Related Videos

Using Retinal Imaging to Study Dementia
09:17

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

21.8K
In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility
07:35

In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility

Published on: April 21, 2022

2.3K

Related Experiment Videos

Last Updated: Sep 25, 2025

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
08:22

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

4.5K
Using Retinal Imaging to Study Dementia
09:17

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

21.8K
In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility
07:35

In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility

Published on: April 21, 2022

2.3K

Area of Science:

  • Ophthalmology
  • Optical Physics
  • Neuroscience

Background:

  • The central macula's optical properties are crucial for visual function.
  • Understanding the microstructural basis of macular optical signals is essential.

Purpose of the Study:

  • To quantify and compare phase retardation distribution in the central macula with Henle fiber layer (HFL) thickness.
  • To validate the Henle fiber layer (HFL) as the dominant source of phase retardation in the macula.

Main Methods:

  • Scanning laser polarimetry (SLP) was used to generate phase retardation maps.
  • Optical Coherence Tomography (OCT) was employed to measure HFL thickness.
  • Correlation analysis was performed between SLP-derived phase retardation and OCT-derived HFL thickness in clinically normal subjects (N=36).

Main Results:

  • A high correlation was observed between phase retardation and HFL thickness within the central 3° of the macula.
  • SLP imaging with both fixed and variable corneal compensation yielded comparable results.
  • Macular cross patterns (fixed compensation) and annulus patterns (variable compensation) accurately represented central macular structures.

Conclusions:

  • The Henle fiber layer (HFL) is the primary contributor to the phase retardation signal in the central macula.
  • SLP is a valuable tool for assessing macular microstructure.
  • Accurate correspondence exists between SLP imaging centers and OCT cross-sectional macular centers.