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Related Experiment Video

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A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules

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Targeted screening in the UK: A narrow concept with broad application.

Anna Bobrowska¹, Molly Murton¹, Farah Seedat²

¹Costello Medical, 50/60 Station Road, Cambridge CB1 2JH, UK.

The Lancet Regional Health. Europe

|May 2, 2022

Summary

A UK report suggests an integrated body for screening recommendations. This review clarifies definitions for targeted screening and related terms, finding overlap that may broaden the new body's scope.

Keywords:

Cascade screening Case finding Population screening Screening Selective screening Targeted screening

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Area of Science:

Public Health
Health Services Research

Background:

A UK report proposed a single integrated advisory body for population and targeted screening programmes.
International consensus on the definition of targeted screening is lacking.

Purpose of the Study:

To identify and compare defining components of various screening terms.
To contribute to an updated definition of targeted screening.

Main Methods:

Systematic review and comparative analysis of definitions for targeted, population, selective, cascade screening, and case finding.
Identification of key differentiating and overlapping components across screening definitions.

Main Results:

Targeted and population screening definitions were distinguished by eligible population.
Targeted and selective screening were found to be conceptually interchangeable.
Cascade screening was primarily used for genetic diseases, with similarities to targeted screening.
Little consensus existed for case finding definitions.

Conclusions:

The review provides an updated definition for targeted screening.
Significant overlap in definition components suggests a broad remit for the proposed integrated advisory body.
Clarifying screening terminology is crucial for effective public health policy and programme implementation.