Related Experiment Video
Updated: Sep 25, 2025

08:43
A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules
Published on: March 10, 2017
10.5K
Targeted screening in the UK: A narrow concept with broad application
Anna Bobrowska1, Molly Murton1, Farah Seedat2
1Costello Medical, 50/60 Station Road, Cambridge CB1 2JH, UK.
The Lancet Regional Health. Europe
|May 2, 2022
Summary
A UK report suggests an integrated body for screening recommendations. This review clarifies definitions for targeted screening and related terms, finding overlap that may broaden the new body's scope.
Area of Science:
- Public Health
- Health Services Research
Background:
- A UK report proposed a single integrated advisory body for population and targeted screening programmes.
- International consensus on the definition of targeted screening is lacking.
Purpose of the Study:
- To identify and compare defining components of various screening terms.
- To contribute to an updated definition of targeted screening.
Main Methods:
- Systematic review and comparative analysis of definitions for targeted, population, selective, cascade screening, and case finding.
- Identification of key differentiating and overlapping components across screening definitions.
Main Results:
- Targeted and population screening definitions were distinguished by eligible population.
- Targeted and selective screening were found to be conceptually interchangeable.
- Cascade screening was primarily used for genetic diseases, with similarities to targeted screening.
- Little consensus existed for case finding definitions.
Conclusions:
- The review provides an updated definition for targeted screening.
- Significant overlap in definition components suggests a broad remit for the proposed integrated advisory body.
- Clarifying screening terminology is crucial for effective public health policy and programme implementation.
Keywords:
Cascade screeningCase findingPopulation screeningScreeningSelective screeningTargeted screeningMore Related Videos
Related Concept Videos
Genetic Screens
5.1K
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
5.1K
Targeted Cancer Therapies
7.9K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.9K

