Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The basement membrane in endometriosis.

J L Evers, D Willebrand

    Fertility and Sterility
    |March 1, 1987
    PubMed
    Summary

    The basement membrane (BM) in endometriosis lesions remains intact, regardless of disease severity. Therefore, examining the BM does not predict prognosis or treatment response in endometriosis patients.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Surgery or embolisation for varicocele in subfertile men.

    The Cochrane database of systematic reviews·2004
    Same author

    Effect of in vitro fertilization treatment and subsequent pregnancy on the protein C pathway.

    British journal of haematology·2001
    Same author

    Androgen, estrogen and progesterone receptor expression in the human uterus during the menstrual cycle.

    European journal of obstetrics, gynecology, and reproductive biology·2001
    Same author

    Endometrial angiogenesis throughout the human menstrual cycle.

    Human reproduction (Oxford, England)·2001
    Same author

    [Macroprolactinemia, a benign form of hyperprolactinemia].

    Nederlands tijdschrift voor geneeskunde·2001
    Same author

    Surgery or embolisation for varicocele in subfertile men.

    The Cochrane database of systematic reviews·2001

    Area of Science:

    • Gynecologic pathology
    • Cancer biology
    • Tissue architecture

    Background:

    • Basement membrane (BM) disruption is linked to cancer metastasis.
    • Previous research suggested potential BM abnormalities in endometriosis, correlating with disease severity.

    Purpose of the Study:

    • To investigate the integrity of the basement membrane (BM) in endometriosis lesions.
    • To determine if BM status has prognostic value for endometriosis, potentially indicating disease severity or treatment response.

    Main Methods:

    • Histological examination of basement membrane (BM) in endometriosis lesions.
    • Analysis of 16 patients across all stages of the revised American Fertility Society (rAFS) classification.

    Main Results:

    • All evaluated endometriosis lesions in all 16 patients exhibited a continuous and intact basement membrane (BM).
    • No correlation was found between BM integrity and the stage of endometriosis (rAFS classification).

    Conclusions:

    • The basement membrane (BM) in endometriosis is consistently intact and does not vary with disease severity.
    • Assessing basement membrane (BM) integrity offers no prognostic advantage for predicting endometriosis outcomes or therapeutic response.

    Related Experiment Videos