Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Opioid Analgesics: Morphine and Other Natural Cogeners01:20

Opioid Analgesics: Morphine and Other Natural Cogeners

392
Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
392
Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

Opioid Analgesics: Synthetic and Semisynthetic Opioids

459
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
459
Analgesia and Pain Management01:25

Analgesia and Pain Management

837
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
837
Opioid Receptors: Overview01:22

Opioid Receptors: Overview

2.1K
Opioid receptors, including the mu (μ, MOR), delta (δ, DOR), and kappa (κ, KOR) types, belong to the rhodopsin family of G protein-coupled receptors. These receptors are located throughout the central and peripheral nervous systems and in non-neuronal tissues such as macrophages and astrocytes. Opioid receptor ligands can be categorized into agonists or antagonists. Highly selective agonists include [d-Ala2, MePhe4, Gly(ol)5]-enkephalin or DAMGO for MOR, [D-Pen2,...
2.1K
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

865
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
865
Drug Control Governance: Regulatory Bodies and Their Impact01:03

Drug Control Governance: Regulatory Bodies and Their Impact

263
Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...
263

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rethinking how we educate our future physicians: the Queen's-Lakeridge Health Medical Degree Family Medicine program: an innovative approach to medical education.

Canadian medical education journal·2026
Same author

Factors influencing PrEP adoption in sexual health clinics within Ontario's public health system: a qualitative study using the Consolidated Framework for Implementation Research (CFIR).

Frontiers in public health·2026
Same author

Exploring youth sport coaches' perceptions of intended outcomes of leadership behaviours.

International journal of sports science & coaching·2026
Same author

Assessing the effectiveness of the transformational coaching workshop using behavior change theory.

International journal of sports science & coaching·2026
Same author

Mise à jour technique n° 466 : Soins virtuels pour la consommation de substances pendant la grossesse et en post-partum.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC·2026
Same author

Technical Update No. 466: Virtual Care for Substance Use in Pregnancy and Post-Partum.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC·2026

Related Experiment Video

Updated: Sep 25, 2025

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum
04:36

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum

Published on: August 5, 2020

4.4K

Developing a Curriculum for Addressing the Opioid Crisis: A National Collaborative Process.

Klodiana Kolomitro1, Lisa Graves2, Fran Kirby3

  • 1Office of Professional Development and Educational Scholarship, Faculty of Health Sciences, Queen's University, Kingston, ON, Canada.

Journal of Medical Education and Curricular Development
|May 2, 2022
PubMed
Summary

A new national curriculum addresses the opioid crisis by educating future physicians on safe prescribing, pain management, and substance use disorder. This initiative ensures consistent training across all Canadian medical schools to combat the growing societal concern.

More Related Videos

Emergency Undocking in Robotic Surgery: A Simulation Curriculum
06:48

Emergency Undocking in Robotic Surgery: A Simulation Curriculum

Published on: May 20, 2018

9.5K
Use of the Operant Orofacial Pain Assessment Device OPAD to Measure Changes in Nociceptive Behavior
12:20

Use of the Operant Orofacial Pain Assessment Device OPAD to Measure Changes in Nociceptive Behavior

Published on: June 10, 2013

21.3K

Related Experiment Videos

Last Updated: Sep 25, 2025

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum
04:36

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum

Published on: August 5, 2020

4.4K
Emergency Undocking in Robotic Surgery: A Simulation Curriculum
06:48

Emergency Undocking in Robotic Surgery: A Simulation Curriculum

Published on: May 20, 2018

9.5K
Use of the Operant Orofacial Pain Assessment Device OPAD to Measure Changes in Nociceptive Behavior
12:20

Use of the Operant Orofacial Pain Assessment Device OPAD to Measure Changes in Nociceptive Behavior

Published on: June 10, 2013

21.3K

Area of Science:

  • Medical Education
  • Public Health
  • Pharmacology

Background:

  • The widespread misuse of opioids presents a significant societal challenge.
  • Inadequate education on safe opioid prescribing, storage, and disposal exacerbates the crisis.
  • Medical education is crucial for equipping future physicians to manage pain and substance use disorders effectively.

Purpose of the Study:

  • To describe the principles and framework for developing a national, competency-based curriculum on pain management and opioid stewardship.
  • To address training gaps in undergraduate medical education concerning the opioid crisis.

Main Methods:

  • Development of a bilingual, competency-based curriculum for Canadian medical students.
  • Utilized the Knowledge to Action theoretical framework for curriculum design.
  • Engaged diverse stakeholder groups throughout the development process.

Main Results:

  • A national curriculum framework was established for implementation in all Canadian medical schools.
  • The curriculum integrates principles of pain management, opioid stewardship, and substance use disorder education.
  • Stakeholder needs and contexts were considered to ensure relevance and applicability.

Conclusions:

  • The developed curriculum standardizes education on pain management and opioid stewardship for future physicians nationwide.
  • This initiative aims to equip physicians with essential knowledge and skills to address the opioid crisis.
  • Consistent training across medical schools will enhance patient care and public safety related to opioid use.