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Updated: Sep 25, 2025

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
Diffuse pulmonary calcification in allergic bronchopulmonary aspergillosis.
Johnny F Jaber1, Lauran Zeineddine2, Divya C Patel1
1Division of Pulmonary, Critical Care, and Sleep Medicine, University of Florida Health, Gainesville, FL, 32608, USA.
Allergic bronchopulmonary aspergillosis (ABPA) is a lung condition often seen in asthma patients. A case study highlights IgE positivity for Aspergillus fumigatus and pulmonary calcifications in a patient with asthma.
Area of Science:
- Pulmonology
- Allergy and Immunology
- Radiology
Background:
- Allergic bronchopulmonary aspergillosis (ABPA) is an inflammatory lung disease.
- ABPA commonly affects individuals with asthma or cystic fibrosis.
- Diagnosis relies on combined clinical, radiographic, and immunologic evidence.
Observation:
- A 64-year-old male with persistent asthma presented with increased cough.
- High-resolution computed tomography (HRCT) revealed diffuse bilateral pulmonary calcifications.
- Laboratory tests showed IgE positivity for Aspergillus fumigatus.
Findings:
- The patient's presentation and diagnostic findings are consistent with ABPA.
- Pulmonary calcifications, while not a classic sign, were noted on HRCT.
- Aspergillus fumigatus specific IgE confirmed sensitization.
Implications:
- This case underscores the importance of considering ABPA in asthma patients with worsening symptoms.
- Radiographic findings like diffuse calcifications may be associated with ABPA.
- Early diagnosis and management of ABPA are crucial for preventing lung damage.
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Published on: September 18, 2021
08:01Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
Published on: March 22, 2012
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