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Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
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Segmental endobronchial valve therapy for a vasculitis-induced emphysema
Christina Bal1, Lisa Göschl2, Ruxandra-Iulia Milos3
1Department of Medicine II, Division of Pulmonology, Medical University of Vienna, Vienna, Austria.
Respiratory Medicine Case Reports
|May 2, 2022
Summary
This study presents a case of emphysema linked to hypocomplementaemic urticarial vasculitis syndrome (HUVS) in a 53-year-old female. Endobronchial valve placement successfully treated the condition, improving lung function and clinical symptoms.
Area of Science:
- Pulmonology
- Rheumatology
- Radiology
Background:
- A 53-year-old female with a history of hypocomplementaemic urticarial vasculitis syndrome (HUVS) and polyarteritis nodosa presented with exertional dyspnea.
- Lung function tests revealed severe obstructive lung disease with significant hyperinflation.
Observation:
- Multi-detector computed tomography (MDCT) and quantitative CT analysis confirmed lower lobe predominant emphysema.
- The emphysema was attributed to vasculitis due to the patient's age, disease history, and exclusion of alpha-1 antitrypsin deficiency.
Findings:
- MDCT identified severe emphysema and hyperinflation in the right lower lobe, specifically segment 8.
- Invasive Chartis® measurement showed no significant collateral ventilation in the isolated segment 8, leading to endobronchial valve placement.
Implications:
- Following endobronchial valve placement, MDCT showed complete collapse of segment 8.
- The intervention resulted in significant clinical benefit and a mild reduction in lung hyperinflation, suggesting a novel treatment approach for vasculitis-associated emphysema.
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