Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Noncovalent Attractions in Biomolecules02:35

Noncovalent Attractions in Biomolecules

56.4K
Noncovalent attractions are associations within and between molecules that influence the shape and structural stability of complexes. These interactions differ from covalent bonding in that they do not involve sharing of electrons.
Four types of noncovalent interactions are hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic interactions.
Hydrogen bonding results from the electrostatic attraction of a hydrogen atom covalently bonded to a strong-electronegative atom like oxygen,...
56.4K
Complexation Equilibria: The Chelate Effect01:19

Complexation Equilibria: The Chelate Effect

699
In complexation reactions, metal atoms or cations interact with ligands to form donor-acceptor adducts called metal complexes. Ligands that bind through one donor site are monodentate, ligands with two donor sites are bidentate, and those with more than two donor sites are polydentate ligands. For example, ethylene diamine is a bidentate ligand that binds through two nitrogen donor atoms, forming a five-membered ring. EDTA is a polydentate ligand that binds through four oxygen and two nitrogen...
699
Intermolecular Forces03:13

Intermolecular Forces

61.8K
Atoms and molecules interact through bonds (or forces): intramolecular and intermolecular. The forces are electrostatic as they arise from interactions (attractive or repulsive) between charged species (permanent, partial, or temporary charges) and exist with varying strengths between ions, polar, nonpolar, and neutral molecules. The different types of intermolecular forces are ion–dipole, dipole–dipole, hydrogen bonds, and dispersion; among these, dipole–dipole, hydrogen...
61.8K
Complexometric Titration: Ligands00:43

Complexometric Titration: Ligands

1.1K
Different monodentate and polydentate ligands are used as complexing agents in complexometric titration reactions. The formation of complexes by mono- and bidentate ligands involves two or more intermediate steps, limiting their use as complexing agents. In comparison, polydentate ligands can form complexes with metal ions in a single-step process, facilitating sharper end points. This means polydentate ligands, such as amino carboxylic acid derivatives, are most commonly employed in...
1.1K
EDTA: Chemistry and Properties01:22

EDTA: Chemistry and Properties

2.3K
Polydentate ligands are most widely used in complexometric titrations because they form more stable complexes with the metal ions than mono- or bidentate ligands due to the chelate effect. Examples of polydentate ligands are ethylenediaminetetraacetic acid (EDTA), crown ethers, and cryptands. The most important feature of optimal polydentate ligands is the ability to form 1:1 complexes in a single-step process. Amino carboxylic acid derivatives are frequently used as complexing agents. EDTA is...
2.3K
Aqueous Solutions and Heats of Hydration02:42

Aqueous Solutions and Heats of Hydration

15.2K
Water and other polar molecules are attracted to ions. The electrostatic attraction between an ion and a molecule with a dipole is called an ion-dipole attraction. These attractions play an important role in the dissolution of ionic compounds in water.
When ionic compounds dissolve in water, the ions in the solid separate and disperse uniformly throughout the solution because water molecules surround and solvate the ions, reducing the strong electrostatic forces between them. This process...
15.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Recyclable Polythioester With α-Gem-Dimethyl Substitution: Instantaneous Crystallization Triggered by Large and Rapid Stretching.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Luminescent Liquid Crystalline Elastomer Promoted Self-Adaptive Smart Active Optical Waveguide with Ultra-Low Optical Loss.

Advanced materials (Deerfield Beach, Fla.)·2025
Same author

Liquid Crystal Promoted Self-Assembly of Statistical Copolymers into Diverse Nanostructures with Precise Dimensions.

Journal of the American Chemical Society·2024
Same author

Adsorption of triblock copolymers confined between two plates: An analytical approach.

The Journal of chemical physics·2024
Same author

Precisely Controllable Artificial Muscle with Continuous Morphing based on "Breathing" of Supramolecular Columns.

Advanced materials (Deerfield Beach, Fla.)·2023
Same author

Morphology and Dynamics of Coexisting Phases in Coacervate Solely Controlled by Crowded Environment.

ACS macro letters·2022
Same journal

High-turnover copper-catalyzed amination of aryl bromides: exploring catalyst and ligand degradation pathways.

RSC advances·2026
Same journal

Sb-based metal oxide and sulfide anode materials for alkali-ion batteries.

RSC advances·2026
Same journal

Directed evolution of a cytochrome P450 monooxygenase for improved perillyl alcohol biosynthesis <i>via</i> a tailored genetically encoded biosensor.

RSC advances·2026
Same journal

Superspin-glass dynamics and magnetic memory in ZnFe<sub>2</sub>O<sub>4</sub> nanoparticles synthesized <i>via</i> a green egg-white-assisted route.

RSC advances·2026
Same journal

Porous and luminescent Dy-doped Co-BTC MOFs for label-free detection of tetracycline and vanadium traces in water.

RSC advances·2026
Same journal

An optimized green simultaneous HPLC analysis of dissolution rate monitoring for valsartan and sacubitril in tablet medications.

RSC advances·2026
See all related articles

Related Experiment Video

Updated: Sep 25, 2025

Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures
08:30

Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures

Published on: January 19, 2019

9.3K

Multivalent counterions induced attraction between DNA polyelectrolytes.

Xu Chen1, Er-Qiang Chen1, Shuang Yang1

  • 1Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Center for Soft Mater Science and Engineering, College of Chemistry and Molecular Engineering, Peking University Beijing 100871 China shuangyang@pku.edu.cn.

RSC Advances
|May 2, 2022
PubMed
Summary
This summary is machine-generated.

Multivalent counterions form 3D Wigner crystals on DNA, inducing electrostatic attraction. Their complex arrangement, not single particles, drives this force between DNA molecules.

More Related Videos

Assembly and Characterization of Polyelectrolyte Complex Micelles
08:44

Assembly and Characterization of Polyelectrolyte Complex Micelles

Published on: March 2, 2020

11.0K
DNA-magnetic Particle Binding Analysis by Dynamic and Electrophoretic Light Scattering
10:35

DNA-magnetic Particle Binding Analysis by Dynamic and Electrophoretic Light Scattering

Published on: November 9, 2017

12.2K

Related Experiment Videos

Last Updated: Sep 25, 2025

Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures
08:30

Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures

Published on: January 19, 2019

9.3K
Assembly and Characterization of Polyelectrolyte Complex Micelles
08:44

Assembly and Characterization of Polyelectrolyte Complex Micelles

Published on: March 2, 2020

11.0K
DNA-magnetic Particle Binding Analysis by Dynamic and Electrophoretic Light Scattering
10:35

DNA-magnetic Particle Binding Analysis by Dynamic and Electrophoretic Light Scattering

Published on: November 9, 2017

12.2K

Area of Science:

  • Biophysics
  • Physical Chemistry
  • Computational Biology

Background:

  • DNA polyelectrolytes are charged molecules crucial in biological systems.
  • Understanding electrostatic interactions is key to DNA structure and function.
  • Multivalent counterions significantly influence polyelectrolyte behavior.

Purpose of the Study:

  • To investigate the electrostatic attraction between two parallel DNA polyelectrolytes.
  • To model the role of multivalent counterions in mediating this attraction at zero temperature.
  • To analyze the impact of counterion crystallization on DNA-DNA interactions.

Main Methods:

  • Utilized the Wigner crystal lattice model for crystallized counterions.
  • Employed the gradient descent method to determine the 3D ground state configuration of counterions.
  • Calculated the interaction forces between two DNA cylinders with divalent and trivalent counterions.

Main Results:

  • Counterions form complex 3D Wigner crystals on DNA surfaces.
  • The specific ground state configuration of counterions dictates the induced attraction.
  • Counterion lines shift to the inner region between DNA cylinders, generating strong attraction.
  • The model's predictions align well with simulation data.

Conclusions:

  • The intricate 3D structure of crystallized counterions is fundamental to DNA attraction.
  • The Wigner crystal model provides a valid framework for studying these systems.
  • Single-particle approximations overestimate the attractive forces between DNA polyelectrolytes.