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Updated: Sep 25, 2025

A High Performance Impedance-based Platform for Evaporation Rate Detection
Published on: October 17, 2016
A high-performance trace level acetone sensor using an indispensable V4C3T MXene.
Wei-Na Zhao1, Na Yun2, Zhen-Hua Dai1
1Guangzhou Key Laboratory of Environmental Catalysis and Pollution Control, Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control, Institute of Environmental Health and Pollution Control, School of Environmental Science and Engineering, Guangdong University of Technology Guangzhou 51006 China zhaowngd@gdut.edu.cn.
A novel V4C3Tx MXene sensor detects low acetone levels at room temperature, offering a promising, rapid point-of-care tool for early diabetes diagnosis. This breakthrough advances MXene applications in gas sensing.
Area of Science:
- Materials Science
- Nanotechnology
- Chemical Sensing
Background:
- Accurate, low-cost acetone detection is crucial for point-of-care diabetes diagnosis.
- Existing sensors often require high operating temperatures or lack selectivity.
- Research into novel MXene materials for gas sensing applications is limited.
Purpose of the Study:
- To synthesize and characterize V4C3Tx MXene for acetone sensing.
- To evaluate the performance of V4C3Tx MXene as an acetone sensor for diabetes diagnosis.
- To investigate the sensing mechanisms using DFT calculations.
Main Methods:
- V4C3Tx MXene synthesized via selective etching of V4AlC3 using aqueous HF.
- Acetone sensing performance evaluated at room temperature (25 °C).
- Density Functional Theory (DFT) calculations used to explore selectivity mechanisms.
Main Results:
- V4C3Tx MXene demonstrated a low detection limit of 1 ppm for acetone.
- The sensor exhibited high selectivity for acetone over water vapor.
- Optimal performance was achieved at a low working temperature of 25 °C.
Conclusions:
- V4C3Tx MXene shows significant promise as a highly selective and sensitive acetone sensor for early diabetes detection.
- This study highlights V4C3Tx MXene as a viable alternative to Ti3C2Tx for gas sensing applications.
- The combined experimental and theoretical approach provides insights for designing advanced MXene-based sensors.

