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Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
Published on: April 26, 2019
Adult Hirschprung's disease diagnosed postoperatively: A case report
Rami Anadani1, Abdallah Aladna1, Sura Radwan1
1Faculty of Medicine, University of Aleppo, Syria.
Background:
Hirschprung's Disease (HD) is a congenital disease where the ganglion cells that innervate the colon fail to migrate. Most cases are diagnosed during childhood, however, in rare cases it can go unnoticed until adulthood.
Case Presentation:
We present a case of a 40-year-old-man who had been managing his chronic constipation with an atypical diet, until he was diagnosed with HD following an emergent abdominal surgery due to unresolved constipation. His diagnosis was delayed mainly out of fear of medical procedures. The surgery was later complicated and followed by a second and a final third and definitive surgery, suitable for the diagnosis of HD.
Conclusion:
HD should be included in the differential diagnosis of constipation even in this age. Also, patient awareness should be increased to ensure better quality of life.
