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Low-grade appendiceal mucinous neoplasm associated with Urothelial carcinoma: A rare case report from Syria
Moatasem Hussein Al-Janabi1, Tala Zidan2, Eman Zidan2
1Department of Pathology, Cancer Research Center, Tishreen University Hospital, Lattakia, Syria.
Introduction:
and importance: Low-grade appendiceal mucinous neoplasm is a rare neoplasm found in the appendix vermiform. Appendiceal mucinous neoplasms are usually seen by accident during investigations or surgeries for other reasons in the abdomen. Low-grade appendiceal mucinous tumors have no specific symptoms.
Case Presentation:
We report an unusual case of a 72-year-old man with low-grade appendiceal mucinous neoplasm, which was found accidently during the investigation of the bladder tumor on a CT scan. Pathological examination of the specimen showed a cystic dilation at the distal tip of the appendix, filled with gelatinous mucus. Microscopically, we found mucinous epithelial proliferation with extracellular mucin.
Clinical Discussion:
Low-grade appendiceal mucinous neoplasm is an uncommon tumor of the appendix. The incidence of low-grade appendiceal mucinous neoplasm is reported to be 1% of all tumors of the gastrointestinal tract and is found in less than 0.3% of appendectomy specimens. Appendiceal mucinous tumors are usually found with no specific symptoms.
Conclusion:
Low-grade appendiceal mucinous neoplasms are rare tumors of the gastrointestinal tract. The appropriate management for this tumor is appendectomy. The most feared complication of these tumors is seeding of mucin into the peritoneal cavity, leading to pseudomyxoma peritonei.
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