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Related Experiment Video

Updated: Sep 25, 2025

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Simultaneous Corneal Topography and Epithelial Thickness Mapping from a Single Measurement Using Optical Coherence

Bartosz L Sikorski1,2

  • 1Department of Ophthalmology, Nicolaus Copernicus University, 9 M. Sklodowskiej-Curie Street, Bydgoszcz 85-309, Poland.

Journal of Ophthalmology
|May 2, 2022
PubMed
Summary
This summary is machine-generated.

The REVO NX OCT device provides repeatable and reproducible corneal epithelial thickness mapping (ETM) and corneal topography. This simultaneous measurement offers a comprehensive view of corneal health and pathology.

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Corneal Science

Background:

  • Corneal epithelial thickness mapping (ETM) is crucial for diagnosing and monitoring various eye conditions.
  • Simultaneous measurement of ETM and corneal topography can provide a more complete understanding of corneal health.

Purpose of the Study:

  • To evaluate the performance of the REVO NX OCT device for corneal epithelial thickness mapping (ETM).
  • To demonstrate the simultaneous measurement of ETM and corneal topography using the REVO NX device.

Main Methods:

  • 137 eyes were scanned using the REVO NX OCT device.
  • ETMs and corneal topography maps were reconstructed from a single measurement.
  • Corneal topography was also performed using Pentacam for comparison.

Main Results:

  • The REVO NX device demonstrated high repeatability and reproducibility for ETMs, with an Intraclass Correlation Coefficient (ICC) of 0.95 for the central sector.
  • The coefficient of variation (CoV) for repeatability was ≤1.55%, slightly higher than some other devices.
  • Superior corneal quadrants were found to be thinner than inferior quadrants.

Conclusions:

  • REVO NX OCT provides reliable and reproducible ETMs in normal eyes.
  • Simultaneous ETM and topography measurements from a single OCT scan eliminate the need for reciprocal centration, ensuring accurate point-to-point correlation.
  • This integrated approach offers a more complete assessment of corneal pathologies.