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Updated: Sep 25, 2025

CRISPR Gene Editing Tool for MicroRNA Cluster Network Analysis
Published on: April 25, 2022
The Emergence of Genome Editing-Innovation Network Dynamics of Academic Publications, Patents, and Business
Natalie Laibach1, Stefanie Bröring2
1Laboratory for Sterol and Terpenoid Metabolism in Plant Development and Stress Responses, Department of Plant Synthetic Biology and Metabolic Engineering, Centre for Research in Agricultural Genomics (CRAG), Barcelona, Spain.
Abstract:
Transformative societal change can both be triggered and influenced by both macro-level political means and the emergence of technologies. Key enabling technologies and therein biotechnology hold the power to drive those changes forward, evolving from breakthrough academic discoveries into business activities. Due to its increasing empirical relevance, we picked genome editing as an example for an emerging technology and extracted publication, patent, and company data from the years 2000 to 2020. By drawing upon social network analysis, we identify major networks and clusters that are dominating the respective time and layer. Based on these networks, we draw vertical connections between scientific knowledge, patented technologies, and business activities to visualize the interlevel relationships between actors through technological development. Thereby, we identify network dynamics of the emergence of genome editing, the most important actors and clusters evolving, and its spread into different areas.
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