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Updated: Sep 25, 2025

Heterogeneous Removal of Water-Soluble Ruthenium Olefin Metathesis Catalyst from Aqueous Media Via Host-Guest Interaction
Published on: August 23, 2018
Influence of water-soluble pillararene hosts on Kemp elimination
Qian Liu1, Xueqi Tian1, Yuhong Shen1
1College of Materials Science and Technology, Nanjing University of Aeronautics and Astronautics Nanjing 211106 China kwang6@nuaa.edu.cn huxy@nuaa.edu.cn.
Abstract:
Since pillar[5]arene was first discovered in 2008, it has developed into a multifunctional supramolecular host. Its application covers many fields from drug delivery and chemical sensing to the construction of molecular machines, and so on. Supramolecular catalysis based on pillar[n]arenes is one of the hot research topics that has emerged in recent years. In this paper, we have synthesized two water-soluble pillar[5]arenes with peripheral rims bearing opposite charges and investigated their influence on Kemp elimination reaction of 1,2-phenylisoxazole derivatives. It is found that both hosts have a moderate rate acceleration effect on the reaction, and the positively charged host H1 has a greater impact on the reaction rate than the negatively charged host H2.
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