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Pediatric Intestinal Pseudo-Obstruction: Progress and Challenges

Marie-Catherine Turcotte1, Christophe Faure1

  • 1Division of Pediatric Gastroenterology, Hepatology and Nutrition, Sainte-Justine University Health Centre, Université de Montréal, Montreal, QC, Canada.

Frontiers in Pediatrics
|May 2, 2022
PubMed

Insights

Pediatric Intestinal Pseudo-Obstruction (PIPO) is a severe form of gastrointestinal dysmotility in children. This review covers PIPO

Area of Science:

  • Pediatric Gastroenterology
  • Gastrointestinal Motility Disorders

Background:

  • Chronic intestinal pseudo-obstruction (CIPO) is a severe gastrointestinal dysmotility.
  • Pediatric Intestinal Pseudo-Obstruction (PIPO) is a distinct entity with unique characteristics.
  • PIPO presents significant morbidity and mortality in the pediatric population.

Approach:

  • This article provides a comprehensive review of PIPO.
  • It covers etiology, pathophysiology, clinical features, diagnosis, and management.
  • Future perspectives for PIPO diagnosis and treatment are discussed.

Key Points:

  • Understanding PIPO's unique etiology and pathophysiology is crucial.
  • Early recognition of clinical features aids timely diagnosis.
  • Multidisciplinary management strategies are essential for improving outcomes.

Conclusions:

  • PIPO requires specialized pediatric gastroenterology expertise.
  • Further research is needed to advance diagnostic and therapeutic approaches.
  • Improved management strategies can mitigate PIPO's impact on affected children.
Abstract

Keywords:
Pediatric Intestinal Pseudo-Obstructionantroduodenal manometryautoimmune GI dysmotilityintestinal transplantationmyopathyneuropathy

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