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Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
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Blood and Nerve Supply to the Bones01:29

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Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
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Pulmonary Tuberculosis II01:28

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
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Related Experiment Video

Updated: Sep 24, 2025

Laminectomy for the Removal of Thoracic Ossification of the Ligamentum Flavum TOLF Using Ultrasonic and Conventional Osteotomes
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[Tuberculous osteomyelitis in the lateral cuneiform bone causing prolonged pain].

Mie Møller1,2,3, Karsten Rex1,3, Anders Koch1,3,4,5

  • 1Center for Sundhedsforskning i Grønland, Ilisimatusarfik.

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|May 2, 2022
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Summary

Tuberculous osteomyelitis, a rare bone infection, was diagnosed in a young man with foot pain. Treatment involved medication and immobilization, successfully managing the tuberculosis.

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Area of Science:

  • Infectious Diseases
  • Orthopedic Surgery
  • Radiology

Background:

  • Tuberculous osteomyelitis is an infrequent manifestation of Mycobacterium tuberculosis infection.
  • Early diagnosis and treatment are crucial for favorable outcomes in bone tuberculosis.

Observation:

  • A 29-year-old male presented with a four-month history of left foot pain, swelling, and discoloration without systemic symptoms.
  • Imaging revealed a pathological fracture of the lateral cuneiform bone and apical pulmonary infiltrates.
  • Bronchoalveolar lavage fluid culture confirmed Mycobacterium tuberculosis.

Findings:

  • The case demonstrates a rare presentation of tuberculous osteomyelitis of the foot.
  • Concurrent pulmonary tuberculosis was identified, highlighting the disseminated nature of the infection.
  • Diagnosis was confirmed through microbiological culture of Mycobacterium tuberculosis.

Implications:

  • This case underscores the importance of considering tuberculosis in the differential diagnosis of osteomyelitis, especially in endemic areas or specific populations.
  • Prompt diagnosis and a comprehensive treatment approach, including antitubercular drugs and immobilization, are essential for managing tuberculous osteomyelitis.
  • Further research into the epidemiology and management of tuberculous osteomyelitis is warranted.