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Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
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Deep unsupervised feature selection by discarding nuisance and correlated features.

Uri Shaham1, Ofir Lindenbaum1, Jonathan Svirsky2

  • 1Yale University, United States of America.

Neural Networks : the Official Journal of the International Neural Network Society
|May 2, 2022
PubMed
Summary
This summary is machine-generated.

This study introduces a new unsupervised feature selection method that effectively handles both correlated and nuisance features in modern datasets. The approach utilizes the Laplacian score criterion and an autoencoder for improved data analysis and clustering performance.

Keywords:
Concrete layerLaplacian scoreUnsupervised feature selection

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Area of Science:

  • Machine Learning
  • Data Science
  • Computer Science

Background:

  • Modern datasets frequently contain correlated and nuisance features, complicating data analysis.
  • Nuisance features, unrelated to underlying data structures, can hinder model performance.
  • Existing methods often struggle to address both correlated and nuisance features simultaneously.

Purpose of the Study:

  • To develop a novel unsupervised feature selection method capable of handling both correlated and nuisance features.
  • To improve the accuracy and efficiency of data analysis and clustering in complex datasets.
  • To provide a robust approach for identifying and selecting relevant features.

Main Methods:

  • A fully differentiable unsupervised feature selection approach is proposed, integrating the Laplacian score criterion.
  • An autoencoder architecture is employed to manage correlated features by reconstructing data from selected features.
  • A concrete layer is utilized to control the number of selected features, simplifying optimization.

Main Results:

  • The proposed method effectively identifies and avoids nuisance features by computing the Laplacian on selected features.
  • Experimental results on real-world datasets show superior performance compared to methods addressing only correlated or nuisance features.
  • State-of-the-art clustering results were achieved, demonstrating the method's efficacy.

Conclusions:

  • The developed unsupervised feature selection technique offers a significant advancement for analyzing datasets with complex feature relationships.
  • The integration of Laplacian score and autoencoder architectures provides a powerful solution for feature selection challenges.
  • The method's ability to handle both correlated and nuisance features leads to improved data representation and downstream task performance.