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Bariatric Weight Loss Surgery Improves Systolic Function in Obese Patients With Heart Failure

Kathir Balakumaran1, Ahmad Jabri1, Faris Haddadin2

  • 1Heart and Vascular Center, Metrohealth Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.

Current Problems in Cardiology
|May 2, 2022
PubMed

Insights

Significant weight loss after bariatric surgery improved heart function in obese patients with heart failure. Older age and female sex predicted recovery of systolic function.

Area of Science:

  • Cardiology
  • Metabolic Surgery
  • Public Health

Background:

  • Obesity is a global health concern, often co-occurring with heart failure with reduced ejection fraction.
  • Previous studies suggest bariatric surgery and subsequent weight loss can improve left ventricular systolic function.

Purpose of the Study:

  • To investigate the impact of bariatric surgery on left ventricular systolic function in morbidly obese patients with heart failure.
  • To identify predictors of systolic function recovery post-bariatric surgery.

Main Methods:

  • Retrospective single-center analysis of patients (2010-2019) with morbid obesity and left ventricular systolic dysfunction.
  • Included patients with BMI >35 kg/m² and obesity-related comorbidity, or BMI >40 kg/m².
  • Assessed systolic function recovery after bariatric surgery and advanced heart failure therapy.

Main Results:

  • Of 190 identified patients, 57 had ejection fraction <40%.
  • Twenty-two patients underwent bariatric surgery, with at least 54.5% showing systolic function recovery.
  • Systolic function recovery was associated with older age (51.58 vs 32.3 years) and predicted by older age and female sex.

Conclusions:

  • Weight loss following bariatric surgery correlates with significant improvement in left ventricular systolic function in patients with obesity and heart failure with reduced ejection fraction.
  • Older age and female sex are predictors of systolic function recovery in this patient population.

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