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Updated: Sep 24, 2025
Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Percutaneous Transcatheter Closure of Post-Myocardial Infarction Ventricular Septal Rupture
Ata Firouzi1, Ehsan Khalilipur1, Mohammad Javad Alemzadeh-Ansari1
1Cardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research, Center, Iran University of Medical Sciences, Tehran, Iran.
Insights
Post-myocardial infarction ventricular septal rupture is a deadly heart complication. This review explores trans-catheter closure as a treatment, focusing on device selection for real-world patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Post-myocardial infarction ventricular septal rupture is a rare but devastating mechanical complication.
- It carries a high morbidity and mortality rate, especially with conservative management.
Purpose of the Study:
- To review the trans-catheter closure approach for post-myocardial infarction ventricular septal rupture.
- To provide guidance on device selection based on real-world patient data.
Main Methods:
- Literature review of trans-catheter closure techniques.
- Analysis of device characteristics and patient factors.
Main Results:
- Trans-catheter closure offers a less invasive alternative to surgery.
- Device selection is crucial and depends on rupture size, location, and patient anatomy.
Conclusions:
- Trans-catheter closure is a viable option for managing ventricular septal rupture post-myocardial infarction.
- Careful device selection can improve outcomes in this critical condition.
Abstract:
Post-myocardial infarction ventricular septal rupture is the most catastrophic mechanical complication with high morbidity and mortality, reaching 94% in patients treated conservatively and 47% in patients undergoing cardiac surgery procedures (30-day mortality). In this review article we tried to review trans-catheter closure approach and explain elaborately device selection based on real-world patients in this fatal complication.
