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Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Aortic dissection in pregnancy and the postpartum period
Melissa Russo1, Mattie Boehler-Tatman2, Catherine Albright3
1Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Women and Infants Hospital, Providence, Warren Alpert Medical School of Brown University, Providence, RI.
Pregnancy-associated aortic dissection (AD) is rare but serious. This review highlights knowledge gaps and proposes future research on clinical management, mental health, and reproductive counseling for AD during pregnancy.
Area of Science:
- Cardiovascular Medicine
- Obstetrics & Gynecology
- Genetics
Background:
- Pregnancy-associated aortic dissection (AD) is a rare but life-threatening condition affecting pregnant individuals.
- Despite its rarity, AD during pregnancy is recognized as a high-priority research topic by the Aortic Dissection Collaborative.
Purpose of the Study:
- To conduct a systematic literature review on pregnancy-associated AD from 1960 to 2021.
- To identify knowledge gaps and future research directions for AD in pregnancy.
Main Methods:
- Systematic literature search across multiple databases (PubMed, MEDLINE, Cochrane, Embase, CINAHL, Web of Science).
- Inclusion criteria: AD in pregnant populations; Exclusion criteria: case reports, conference abstracts, non-English articles.
- Final review included 68 articles after duplicate removal and full-text assessment.
Main Results:
- Analysis focused on the timing of AD during pregnancy, AD type, and management strategies.
- Identified significant gaps in understanding clinical management, post-AD mental health outcomes, reproductive/genetic counseling, and contraception.
Conclusions:
- Further research is crucial to improve the management and outcomes of pregnancy-associated AD.
- Recommendations include establishing an international registry and conducting mixed-methods studies on psychosocial factors and support group efficacy.
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