[On the long-term alternative immunochemotherapy against gastric cancer]

To evaluate the effectiveness of adjuvant chemotherapy to prevent the recurrence of cancer, followed by surgical removal, controlled trial studies have been performed since 1956 as a combined program of many medical centers and hospitals. Recently, to prevent the destruction of the host defence mechanisms, non-specific immunotherapy has been used during the same time. In this report, the usefulness of "long-term alternative immunochemotherapy" in gastric cancer is mentioned in the clinical as well as in the experimental field. It is still too soon to find the best combination of these drugs and the best order in which to administer them.