Related Experiment Video
Updated: Sep 24, 2025

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
Published on: August 25, 2017
CT-Based Commercial Software Applications: Improving Patient Care Through Accurate COPD Subtyping.
Jennifer M Wang1, Sundaresh Ram2, Wassim W Labaki1
1Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI, USA.
Quantitative computed tomography (QCT) can help classify chronic obstructive pulmonary disease (COPD) phenotypes. Automated CT software offers valuable metrics for research and clinical applications in COPD management.
Area of Science:
- Pulmonology and Medical Imaging
Background:
- Chronic obstructive pulmonary disease (COPD) exhibits heterogeneous clinical presentations and progression, making patient outcomes difficult to predict using standard lung function tests.
- Accurate COPD classification is crucial for tailoring therapies, monitoring treatment efficacy, and enhancing patient-centered outcomes.
Purpose of the Study:
- To review commercial quantitative computed tomography (QCT) software platforms for assessing COPD phenotypes.
- To explore the technologies, metrics, clinical correlations, and applications of these QCT tools.
Main Methods:
- Review of commercial automated CT software packages.
- Focus on QCT techniques analyzing airway anatomy, lung density, and vascular morphology in COPD patients.
Main Results:
- Commercial QCT software provides automated analysis of key features for COPD phenotyping.
- These tools generate metrics with demonstrated clinical correlations and applications in research settings.
Conclusions:
- QCT software shows significant promise for improving COPD classification and patient management.
- Wider adoption in routine diagnostics and treatment planning is needed to fully realize the potential of these advanced imaging tools.
Related Concept Videos
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Statistical Software for Data Analysis and Clinical Trials
Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation
COPD: Management Using Bronchodilators and Corticosteroids
Chronic Obstructive Pulmonary Disease-I: Introduction
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...

