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Updated: Sep 24, 2025
07:11
Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
Published on: October 28, 2020
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Association between metabolic syndrome and left ventricular geometric change including diastolic dysfunction
Seung-Jae Lee1, Hyunah Kim1, Byeong Kil Oh1
1Division of Cardiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
Clinical Cardiology
|May 3, 2022
Summary
Metabolic syndrome (MetS) is linked to left ventricular diastolic dysfunction (LVDD), particularly in men. Increasing MetS components, specifically high triglycerides and waist circumference, elevate LVDD risk in males.
Area of Science:
- Cardiology
- Metabolic Health
- Echocardiography
Background:
- Investigated the link between metabolic syndrome (MetS) components and left ventricular (LV) geometric changes.
- Focused on diastolic dysfunction in a large cohort of healthy adults.
Purpose of the Study:
- To determine the association between individual MetS components and LV diastolic dysfunction.
- To analyze the impact of MetS on cardiac structure and function.
Main Methods:
- Analyzed echocardiography data from 148,461 adults in a health-screening program.
- Identified LV relaxation markers and assessed MetS components.
- Utilized univariate and multivariate regression models for analysis.
Main Results:
- LV diastolic dysfunction (LVDD) was more prevalent in the MetS group (0.56% vs. 0.27%).
- MetS was associated with LVDD (OR 1.350), especially in men (OR 1.3).
- Triglycerides and waist circumference were significant independent risk factors for LVDD in men.
Conclusions:
- Metabolic syndrome increases the risk of left ventricular diastolic dysfunction.
- The association between MetS and LVDD is more pronounced in men.
- Elevated triglycerides and increased waist circumference are key risk factors for LVDD in men.
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