Related Experiment Video
Updated: Sep 24, 2025

Exploring the Regulation of Lipid Droplet Catabolism through Lipophagy
Published on: January 31, 2025
[Exercise regulates lipid metabolism via lipophagy and its molecular mechanisms]
Meng-Ying Li1, Ling-Jie Li2, Chun-Wei Ma1
1School of Kinesiology, Shanghai University of Sport, Shanghai 200438, China.
Abstract:
Lipophagy is a kind of selective autophagy, which can selectively identify and degrade lipid droplets and plays an important role in regulating cellular lipid metabolism and maintaining intracellular lipid homeostasis. Exercise can induce lipophagy and it is also an effective means of reducing body fat. In this review, we summarized the relationship between exercise and lipophagy in the liver, pancreas, adipose tissue, and the possible molecular mechanisms to provide a new clue for the prevention and treatment of fatty liver, obesity and other related metabolic diseases by exercise.
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